An exhaustive guide to the handling, interpretation, and application of information contained in the sequence of DNA, this resource is an essential tool for academic, industrial, and private researchers in the field of life sciences. Information on applying DNA sequence information in genetics, using DNA sequence analysis and recognition software for DNA structural elements, and predicting and modeling higher order DNA structures is provided along with links to relevant web sites and an explanation of their corresponding interfaces. Chapters are formatted as frequently asked questions regarding structure, function, regulation, and the evolution of coding and non-coding DNA sequences, and reflects previously probed and published strategies for data mining and interpretation.

(Editor) Dr. Markoff is a biochemist at the Institute of Medical Biochemistry at the University of Muenster in Germany. He is among the pioneers to use protein structure and conformation prediction tools to visualize the effects of potentially pathogenic amino acid replacement mutations.